Chapter No 19 :Epigenetic Regulation of Gene Expression (105 MCQ`S)

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  1. The study of the effects of reversible chemicals modifications to DNA and histones on the pattern of gene expression
    1. Epigenetics
    2. Eugenetics
    3. Depression
    4. None of these
    5. Show Answer
      Answer: A
      Explanation:
      • N/A
  2. DNA methylation takes place
    1. After DNA replication
    2. During cell differentiation
    3. Before DNA replication
    4. Both a and b
    5. Show Answer
      Answer: D
      Explanation:
      • N/A
  3. Epigenetic mechanism/mechanisms
    1. Addition of methyl group to DNA
    2. Removal of methyl group from DNA
    3. Chromatin remodeling
    4. All of these
    5. Show Answer
      Answer: D
      Explanation:
      • N/A
  4. During DNA methylation, methyl group attaches with________on the 5-carbon
    1. Guanine
    2. Cytocine
    3. Thymine
    4. Adenine
    5. Show Answer
      Answer: B
      Explanation:
      • N/A
  5. In human, the 5-methylcytocine (5mC) is present in about________percent of the genomic DNA
    1. 3.5
    2. 2.5
    3. 1.5
    4. 0.5
    5. Show Answer
      Answer: C
      Explanation:
      • N/A
  6. Methylation of DNA takes place almost exclusively on cytocine bases located adjacent to a _________base
    1. Guanine
    2. Cytocine
    3. Thymine
    4. Adenine
    5. Show Answer
      Answer: A
      Explanation:
      • N/A
  7. Methylation of DNA takes place at__________dinucleotide
    1. CpG
    2. CpT
    3. CpA
    4. CpC
    5. Show Answer
      Answer: A
      Explanation:
      • N/A
  8. CpG islands are located in
    1. Promoter
    2. Upstream
    3. Downstream
    4. Both a and b
    5. Show Answer
      Answer: D
      Explanation:
      • N/A
  9. CpG islands and promoters adjacent to______________genes are unmethylated, making them available for transcription
    1. Essential
    2. Housekeeping
    3. Cell-specific
    4. All of these
    5. Show Answer
      Answer: D
      Explanation:
      • N/A
  10. CpG islands and methylated cpG sequences within promoters are transcriptionally________
    1. Active
    2. silenced
    3. Smart
    4. None of these
    5. Show Answer
      Answer: B
      Explanation:
      • N/A

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